氨基末端脑钠肽前体水平对冠心病合并代谢综合征患者远期心血管事件的预测意义

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目的 探讨血浆氨基末端脑钠肽前体(NT-proBNP)对冠心病合并代谢综合征患者远期心血管事件的预测意义.方法 经冠状动脉造影证实的165例冠心病合并代谢综合征患者,在入院时测定NT-pro 水平,通过2年随访,观察其对远期心血管事件的预测意义.结果 冠心病合并代谢综合征患者NT-proBNP水平显著高于合并稳定型心绞痛组(P<0.01).2年后共发生心血管事件45例,调整了高血压、糖尿病、吸烟、高敏C反应蛋白等传统危险因素后,Cox风险回归提示NT-proBNP> 111.58 ng/L是预测远期心血管事件的独立危险之一(相对危险度2.67,P<0.01).结论 NT-proBNP是冠心病合并代谢综合征患者发生远期心血管事件的独立危险因素之一.
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