例1 女性,11岁。因出生后至今全身皮肤不出汗,头发稀少,无眉毛。患儿系第1胎,(早产妊娠8个月时出生),出生后头发稀少,幼儿时每逢夏季经常发生不明原因的高热,每次发热都经输液等治疗后体温才能降至正常。父母亲无类似病史,也非近亲结婚,查体发现患儿发育短小,智力正常,头顶部毛发稀少,呈片状分布,头枕部无毛发,前额突出,面部下半部狭窄, Example 1 Female, 11 years old. Due to the body after birth does not sweat, scarce hair, no eyebrows. Children born in the first child, (premature birth at 8 months of pregnancy), after birth hair scarce, often in infants every summer, unexplained fever, each fever after infusion and other treatment can be reduced to normal body temperature. Parents have no similar history, but also non-relatives married, physical examination found that children with short development, mental normal, thin hair at the top of the head, was flaky distribution, head and hair without hair, prominent forehead, lower face half of the narrow,