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本文总结了对于39例中重度再生障碍性贫血(再障)应用重组粒细胞集落刺激因子(rhG-CSF)后的临床效果。39例患者中特发性再障36例。肝炎后再障2例,药物引起的再障1例。用药前周围血中性粒细胞<0.5×10~9/L者36例,<1.0×10~9/L且持续1个月以上者3例。全部病例中未经任何治疗者6例,既往曾用强的松、蛋白同化激素,抗淋巴细胞球蛋白等治疗者33例。本次治疗前病程1~1705周(中数25周)
This article summarizes the clinical results of 39 cases of moderate and severe aplastic anemia (aplastic anemia) application of recombinant granulocyte colony stimulating factor (rhG-CSF). 39 cases of idiopathic aplastic anemia in 36 cases. Aplastic anemia after 2 cases, drug-induced aplastic anemia in 1 case. 36 cases of peripheral blood neutrophils <0.5 × 10 ~ 9 / L before treatment, <1.0 × 10 ~ 9 / L for 1 month or more in 3 cases. All cases without any treatment in 6 cases, had used prednisone, protein anabolic hormone, anti-lymphocyte globulin and other treatment of 33 cases. The course of treatment before 1 ~ 1705 weeks (median 25 weeks)