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目的探讨C-反应蛋白(CRP)与心肌酶谱检查在小儿肺炎中的诊断价值。方法回顾性分析该院儿科2011年9月~2014年6月收治的120例肺炎患儿的临床资料,其中细菌性肺炎40例、支原体肺炎40例、病毒性肺炎40例;另选取同期40例健康儿童作为对照组,比较4组研究对象入院就诊时的CRP、白细胞计数(WBC)及心肌酶含量差异。结果 4组研究对象入院时的WBC、CRP检查值比较,差异有统计学意义(P<0.05),细菌性肺炎组患儿的WBC〔(13.8±4.3)109/L〕、CRP〔(67.4±19.5)mg/L〕均显著高于其他3组,支原体肺炎组患儿与病毒性肺炎组患儿WBC比较,差异无统计学意义(P>0.05),但均显著高于对照组小儿(P<0.05);支原体肺炎组患儿CRP值>病毒性肺炎组>对照组,3组间两两比较差异有统计学意义(P<0.05)。4组研究对象的肌酸激酶(CK)含量比较,差异无统计学意义(P>0.05),支原体肺炎组患儿的肌酸激酶同工酶(CK-MB)〔(38.7±8.4)IU/L〕、天冬氨酸氨基转移酶(AST)〔(53.8±16.4)IU/L〕、乳酸脱氢酶(LDH)〔(308.9±48.4)IU/L〕均显著高于其他3组(P<0.05)。结论早期检测WBC、CRP能够对肺炎患儿进行鉴别诊断,早期检测心肌酶含量可以判定和预测肺炎对患儿心肌的损害及其严重程度。
Objective To investigate the diagnostic value of C-reactive protein (CRP) and myocardial enzymes in children with pneumonia. Methods The clinical data of 120 children with pneumonia admitted from September 2011 to June 2014 in our hospital were retrospectively analyzed. Among them, 40 were bacterial pneumonia, 40 were mycoplasma pneumonia and 40 were viral pneumonia. Another 40 patients Healthy children as control group, compared the four groups of subjects on admission CRP, WBC and myocardial enzyme content differences. Results There were significant differences in WBC and CRP in admission between the four groups (P <0.05). WBC (13.8 ± 4.3) 109 / L in children with bacterial pneumonia and CRP 〔(67.4 ± 19.5) mg / L] were significantly higher than those in the other three groups. There was no significant difference in WBC between children with mycoplasma pneumonia and children with viral pneumonia (P> 0.05), but both were significantly higher than those in the control group <0.05). The CRP value of viral pneumonia group> control group in children with mycoplasma pneumonia was significantly different (P <0.05). There were no significant differences in creatine kinase (CK) contents between the four groups (P> 0.05). CK-MB in mycoplasma pneumonia group (38.7 ± 8.4) IU / L], AST (53.8 ± 16.4 IU / L) and lactate dehydrogenase (LDH) 〔(308.9 ± 48.4) IU / L〕 were significantly higher than the other three groups <0.05). Conclusion Early detection of WBC and CRP can differentiate children with pneumonia. Early detection of myocardial enzyme content can determine and predict the damage and severity of myocardium in children with pneumonia.