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研究绿茶儿茶素（Ｇｒｅｅｎｔｅａｃａｔｅｃｈｉｎ，ＧＴＣ）在小鼠体内对淋巴瘤Ｌ５１７８Ｙ免疫反应的影响。结果表明，ＧＴＣ能（１）促进对Ｌ５１７８Ｙ产生免疫反应的小鼠脾细胞的特异性增殖，这一作用在ＧＴＣ２ｍｇ／ｄ灌喂的小鼠尤为显著，增殖作用比不灌喂的高６～１０倍；（２）加强特异性ＣＴＬ的诱导；（３）增加ＩＬ－２分泌和ＩＬ－２ｍ－ＲＮＡ表达；（４）增强ＮＫ细胞活性。ＧＴＣ的上述作用可能与降低巨噬细胞的抑制活性有关。
The effect of green teacatechin (GTC) on the immune response of lymphoma L5178Y in mice was investigated. The results showed that GTC could (1) promote the specific proliferation of splenocytes in mice immunized with L5178Y. This effect was particularly marked in mice fed with GTC 2 mg/d, and the proliferation was 6 to 10 higher than that of non-inoculated mice. (2) increase the induction of specific CTLs; (3) increase IL-2 secretion and IL-2m-RNA expression; (4) enhance NK cell activity. The above effects of GTC may be related to the decrease of macrophage inhibitory activity.