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目的:探讨抗结核药致药物性肝炎的发病规律与临床特点。方法:回顾性调查分析2008年1月至2010年6月以来本单位治疗的肺结核患者在抗结核治疗中出现肝损害的临床相关因素以及误诊情况。结果:抗结核药致药物性肝炎与患者年龄、结核病分型、用药时间、初复治结核及合并其它疾病等相关,治疗预后较好。结论:认识影响抗痨致药物性肝炎有多种因素,定时检测肝功能,尽早发现、早诊断、早治疗,有利于抗痨疗程完成。
Objective: To investigate the incidence of anti-TB drug-induced hepatitis and clinical features. Methods: Retrospective investigation was conducted to analyze the clinical factors and misdiagnosis of liver damage in TB patients treated by this unit from January 2008 to June 2010. Results: Anti-TB drugs induced drug-induced hepatitis was associated with patient’s age, tuberculosis typing, medication duration, initial treatment of tuberculosis and other complicated diseases. The prognosis was good. Conclusion: There are many factors that affect the antihepatitis drug-induced hepatitis, regular detection of liver function, early detection, early diagnosis and early treatment, is conducive to the completion of anti-tuberculosis treatment.