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目的探索铝的神经毒性和职业性铝作业工人的心理和神经行为功能改变。方法采用ＷＨＯ推荐的神经行为测试组合，对１０３名铝作业工人和６４名对照工人进行心理状况调查和神经行为功能测试，同时对作业环境空气中铝浓度和作业工人尿铝水平进行测定。结果铝作业工人尿铝含量明显高于对照组工人，两组差异有显著性。铝接触工龄＞１０年的工人紧张、忧郁、愤怒、疲劳和困惑情感得分均高于对照组工人；手提转捷度、数字译码和目标追踪得分显著降低。而铝接触工龄≤１０年的工人除目标追踪得分明显降低外，未发现其他行为功能和心理指标改变。结论长期职业性铝接触可以引起作业工人出现明显的心理状态、神经运动速度和准确性以及运动协调能力的改变。
Objective To explore the neurotoxicity of aluminum and the psychological and neurobehavioral changes of occupational aluminum workers. Methods According to the combination of neurobehavioral tests recommended by the WHO, 103 aluminum working workers and 64 control workers were tested for psychological status and neurobehavioral function. The concentrations of aluminum in working air and urine aluminum level of workers were also measured. Results Aluminum workers urine aluminum content was significantly higher than the control group workers, the difference was significant. Workers exposed to aluminum for more than 10 years had significantly higher scores on stress, depression, anger, fatigue and confusion than workers in the control group; hand-turning speed, number decoding and target tracking scores were significantly lower. However, the workers exposed to aluminum with a working age of less than 10 years did not find any changes in other behavioral functions and psychological indicators except that their target tracking scores decreased significantly. Conclusion Long-term occupational exposure to aluminum can cause obvious mental state, speed and accuracy of nerve movement and changes of motor coordination ability.