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本研究用五种常见铝油(氯化铝、硫酸铝、铝酸钠、草酸铝和柠檬酸铝)检测其细胞遗传毒理学效应,以便对铝的细胞遗传毒理作用机制和遗传危险性评估提供科学依据。结果示铝盐对小鼠骨髓细胞染色体有致畸变作用;可致小鼠精子畸形;有抑制小鼠骨髓细胞的分裂作用和人体外周血淋巴细胞生长作用,具有一定细胞毒性和抑制淋巴细
In this study, five common aluminum oils (aluminum chloride, aluminum sulfate, sodium aluminate, aluminum oxalate and aluminum citrate) were used to test their cytogenetic toxicology in order to evaluate the mechanism of cytogenetic toxicology and genetic risk assessment of aluminum Provide a scientific basis. The results showed that aluminum salt on mouse bone marrow cells have chromosome aberration induced; can cause sperm deformity in mice; can inhibit mouse bone marrow cell division and human peripheral blood lymphocyte growth, with certain cytotoxicity and inhibit lymphocyte