目的比较原发性遗尿儿童与非遗尿儿童go/no-go联想任务执行测试结果差异,探讨原发性遗尿儿童的反应抑制功能状况,为临床原发性遗尿儿童选择治疗方案提供参考。方法选择2015年1-8月在上海儿童医学中心发育行为儿科门诊就诊的、门诊资料完整的原发性遗尿儿童35例,设为观察组,选取同期健康体检的6~11岁儿童35例作为对照组。两组受试儿童均通过go/no-go联想任务执行测试对其反应抑制功能进行评估,对两组受试儿童go/no-go联想任务执行的go正确率、no-go正确率、go反应时间、no-go反应时间进行比较。结果两组受试儿童月龄、性别、体重、体质量指数(BMI)、遗尿频次、遗尿病程、语言智商得分、操作智商得分及总智商得分比较差异均无统计学意义(P>0.05)。两组受试儿童的go正确率、no-go正确率比较差异无统计学意义(P>0.05);但观察组儿童go反应时间、no-go反应时间较对照组儿童明显增加(P<0.05)。提示观察组儿童反应抑制功能存在缺陷。结论原发性遗尿儿童反应抑制功能较正常儿童存在缺陷,对原发性遗尿儿童进行反应抑制相关项目训练,可作为治疗遗尿的新靶点,结合其他治疗方案,可排除患儿因反应抑制功能缺陷而导致的药物及行为方式训练治疗复发率高、疗效不稳定的缺点,具有较高的临床价值。 Objective To compare the results of test results of go / no-go associative task between primary enuresis children and non-enuresis children, and to investigate the status of response inhibition in primary enuresis children, so as to provide reference for clinical treatment of children with primary enuresis. Methods From January to August 2015, 35 cases of primary enuresis with outpatient pediatric clinics in Shanghai Pediatric Medical Center for Developmental Behavior Pediatric Clinic were selected as observation group and 35 healthy children aged 6 to 11 were selected as the control group Control group. The two groups of children under test go / no-go Lenovo task execution test to evaluate its response to inhibition of the two groups of children go / no-go Lenovo task execution go correct, no-go correct rate, go Reaction time, no-go reaction time for comparison. Results There was no significant difference in age, sex, weight, body mass index (BMI), frequency of enuresis, duration of enuresis, language IQ score, operation IQ score and total IQ score between the two groups (P> 0.05). There was no significant difference in the go correct rate and no-go correct rate between the two groups (P> 0.05). However, the reaction time and no-go reaction time of go group in the observation group were significantly higher than those in the control group (P <0.05 ). Suggesting that the observation group of children’s response to inhibition of defects. CONCLUSIONS: Primary urinary incontinence is more deficient than normal children in response inhibition. Primary urinary incontinence can be used as a new target for treatment of patients with primary urinary nocturnal enuresis. In combination with other treatment options, Defects and lead to drugs and behavioral training to treat recurrence rate is high, the instability of the shortcomings, with high clinical value.