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目的:探讨对硫磷、敌敌畏、甲胺磷、甲拌磷、乐果以及氧乐果6六种急性有机磷农药引发呼吸衰竭中毒的影响因素和发生率。方法:选取2010年6月至2012年12月我院收治的急性有机磷农药患者150例进行分析,依据中毒农药类型,将150例患者分为六组,对硫磷中毒患者为a组,敌敌畏重度患者为b组,甲胺磷中毒患者为c组,甲拌磷中毒患者为d组,乐果中毒患者为e组,氧乐果中毒患者为f组,分析六组患者呼吸衰竭发生率和影响因素。结果:六组患者呼吸衰竭发生率差异显著,p<0.05;性别和年龄对于患者是否出现呼吸衰竭没有影响。结论:有机磷中毒后患者出现呼吸衰竭的发生率随着中毒有机磷种类不同而不同,有机磷农药的毒理学特性是导致呼吸衰竭发生率出现一定差异的基本因素。明确各种有机磷农药至呼吸衰竭的发生率,有利于急性有机磷农药中毒患者临床治疗中对呼吸衰竭病症做出预见性治疗措施,促进急性有机磷农药中毒患者临床治疗效果的提高。
Objective: To investigate the influencing factors and incidence of poisoning caused by respiratory failure in parathion, dichlorvos, methamidophos, phorate, dimethoate and omethoate six acute organophosphorus pesticides. Methods: 150 cases of acute organophosphorus pesticide admitted in our hospital from June 2010 to December 2012 were selected for analysis. According to the type of pesticide poisoning, 150 patients were divided into six groups, parathion poisoning patients were a group, dichlorvos Severe patients were b group, methamidophos patients were c group, phorate patients d group, dimethoate poisoning patients e group, omethoate patients f group, analysis of the six groups of patients with respiratory failure rate and Influencing factors. Results: There was a significant difference in the incidence of respiratory failure between the six groups (p <0.05). Gender and age had no effect on whether patients had respiratory failure. Conclusion: The incidence of respiratory failure in patients with organophosphate poisoning varies with different types of organophosphate poisoning. The toxicological characteristics of organophosphorus pesticide are the basic factors that cause some differences in respiratory failure. To clarify the incidence of various organophosphorus pesticides to respiratory failure is conducive to the treatment of patients with acute organophosphorus pesticide poisoning in the treatment of respiratory failure to make predictive measures to promote the clinical efficacy of acute organophosphorus pesticide poisoning patients.