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灭虫宁是用于驱除钩虫的药物,它的化学全名为N-苄基-N,N-二甲基-N-2-苯氧基乙基铵羟萘酸盐,简称“羟萘酸酚乙铵”或“羟萘酸苄酚宁”。目前我国已大量生产,以供医疗上的需要。灭虫宁为一种广谱驱虫药,除对钩虫有显著效果外,对蛔虫、蛲虫、鞭虫也有一定作用。惟疗效以钩虫为佳,蛔虫次之,蛲虫、鞭虫又次之。在驱钩方面,证明疗效高于四氯乙烯和溴萘酚。灭虫宁用于驱治钩虫病,单剂一次顿服就能奏效;服药后不必再服泻盐,因为灭虫宁对肠道粘膜有轻微刺激,能增进肠的蠕动,促使已死虫体随大便排出。灭虫宁毒性較低,小白鼠口服半数致死量(LD_(50))为5000～7350毫克/公斤(指游离硷重)。药物反应主要有恶心、呕吐、腹部不适、腹泻、腹痛等肠胃道反应。有时也可发现一过性便血者。头痛、头昏等全身性反应则比较少见。
Pest control is used to get rid of hookworm drugs, its full chemical name is N-benzyl-N, N-dimethyl-N-2-phenoxyethyl ammonium hydroxynaphthalene, referred to as “hydroxynaphthalene Acid phenol ethoxylate ”or “ hydroxynaphthoin ”. At present, China has mass-produced for medical needs. Pest control rather as a broad-spectrum de-worming drugs, in addition to the hookworm have a significant effect, the roundworm, pinworm, whipworm also have a role. However, the efficacy of hookworms is better, roundworms, pinworm, whipworm again. In the drive hook, the proof of efficacy than tetrachlorethylene and bromonaphthol. Pest control Ningzuo for the treatment of hookworm disease, a single dose of Dayton clothing can be effective; no longer need to take Epsom salt medication, because Pest control of the intestinal mucosa slightly stimulated to promote intestinal peristalsis, prompting dead insects Body discharge with the stool. Insect toxicity rather low, white mice oral LD50 (LD_ (50)) of 5000 ~ 7350 mg / kg (referring to free alkaline weight). The main drug reactions are nausea, vomiting, abdominal discomfort, diarrhea, abdominal pain and other gastrointestinal reactions. Occasionally can also be found in those who have blood in the stool. Headache, dizziness and other systemic reactions are relatively rare.