男女性间生理差异影响药物活性,包括药动学和药效学。女性药动学受体质量较低、肠蠕动较慢、肠酶活性较低和肾小球滤过率较低的影响。若属需空胃吸收的药物,女性进餐和服药间隔需延长,因女性胃排空要延缓。其他生理差异也可影响用药剂量。例如,由于女性肾清除较慢,有些经肾排泄 Physiological differences between men and women affect drug activity, including pharmacokinetics and pharmacodynamics. Female pharmacokinetics receptor lower quality, slower gut motility, lower intestinal enzyme activity and lower glomerular filtration rate. In the case of empty stomach absorption of drugs, women need to eat and medication intervals need to be extended because of gastric emptying to be delayed. Other physiological differences can also affect the dosage. For example, some are excreted via the kidneys due to slower female kidney clearance