One form of energy generation that is expected to be on the rise in the next several decades is thermoelectric power generation (TEPG) which converts heat directly to electricity. Compared with other methods, TEPG possesses the salient features of being compact, light-weighted,noiseless in operation, highly reliable, free of carbon dioxide emission and radioactive substances. Low current conversion efficiency and high cost, however, are some of the disadvantages. Use of TEPG is therefore justified to hightech applications associated with aerospace, military operation,tel-communication and navigation, instrumentation of unmanned vehicles monitored from remote locations. Moreover, TEPG does not contribute to the depletion of natural resource and pollution of the environment such as climate warming that has been a concern in recent times. This work is concerned with providing an overview of the state of the art of TEPG with emphases placed on assessing its current and potential application. Pointed out are the ways to fabricate high performance thermoelectric material, a hurdle to overcome for the enhancement of TEPG device efficiency.