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人类巨细胞病毒(HCMV)是一种广泛传播的致病因子,孕妇感染可导致胎儿先天畸形、流产和死胎等。为探讨大连地区孕妇HCMV 活动感染及母婴传播的关系,我们对1119例孕妇血清中 HCMV 特异 IgM 抗体及41例新生儿尿液 HCMV-DNA 进行了检测。1 对象与方法1.1 对象大连市210医院及妇产医院中晚期孕妇1119例,于门诊常规产前检查时抽取静脉血留血清待测。新生儿41例,在出生1周内留新鲜尿液待测。
Human cytomegalovirus (HCMV) is a widely transmitted virulence factor that can cause congenital malformations, abortions and stillbirths in pregnant women. In order to explore the relationship between HCMV infection and maternal-to-infant transmission in pregnant women in Dalian, 1198 HCMV-specific IgM antibodies in serum and 41 HCMV-DNA in urine of newborn infants were detected. 1 Subjects and Methods 1.1 Object Dalian 210 Hospital and Obstetrics and Gynecology Hospital in 1119 cases of late pregnant women, routine outpatient prenatal examination venous blood serum taken for testing. 41 cases of newborns, fresh urine to be tested within 1 week of birth.