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本实验的目的是探讨促甲状腺素释放激素(TRH)的中枢加压作用和对心脏活动的影响及其机制。 一、实验方法 1.方法:家兔30只,体重1.8～2.3kg。乌拉坦1g/kg静脉注射麻醉,按Sawyer兔脑图谱作侧脑室插管;暴露心脏,自然呼吸;主动脉根部套一探头,连接电磁流量计,左颈动脉插管,自心尖作左心室插管,分别与压力换能器相连,同步记录于RM-6200型多道生理记录仪上。测定下列参数:动脉收缩压(AMP)、动脉舒张压(DAP)、平均动脉血压(AMP)、左心室收缩压力峰值(LVSP)、
The purpose of this experiment is to investigate the central pressure effect of thyrotropin-releasing hormone (TRH) and its effect on cardiac activity and its mechanism. First, the experimental method 1. Methods: 30 rabbits, weighing 1.8 ~ 2.3kg. Urazan 1g / kg intravenous anesthesia, according to Sawyer rabbit brain atlas for the lateral ventricle intubation; exposure to the heart, natural breathing; aortic root set a probe, connected to the electromagnetic flowmeter, left carotid artery catheterization, Tube, respectively, connected with the pressure transducer, simultaneously recorded in the RM-6200 multi-channel physiological recorder. The following parameters were measured: arterial systolic pressure (AMP), arterial diastolic pressure (DAP), mean arterial pressure (AMP), left ventricular systolic pressure peak (LVSP)