黄色肉芽肿性胆囊炎是一种少见类型的胆囊炎,发病机制尚未完全清楚。因其胆囊壁弥漫性不均匀增厚及向周围器官浸润等特点而与胆囊癌难以鉴别,其病史体征、肿瘤标记物及影像学特点均不典型,加之部分病例合并有胆囊癌,术前难以做出确定性诊断。术前和术中细针穿刺冰冻病理学检查的诊断率相对较高,对手术方式选择有重要参考意义。因腹腔镜胆囊切除术的术中中转开腹率及并发症发生率很高,故临床多选择开腹胆囊切除术,依术中所见及冰冻病理学检查结果选择恰当的术式。 Yellow granulomatous cholecystitis is a rare type of cholecystitis, the pathogenesis is not yet fully understood. Because of its uneven thickening of the gallbladder wall and infiltration to the surrounding organs and other characteristics of the gall bladder cancer is difficult to identify the history and signs, tumor markers and imaging features are not typical, in addition to some cases with gallbladder cancer, preoperative difficult Make a definitive diagnosis. The diagnostic rate of preoperative and intraoperative fine needle aspiration cryopathology is relatively high, which has important reference value for the selection of operative methods. Due to laparoscopic cholecystectomy intraoperative conversion rate of laparotomy and the high incidence of complications, so the clinical choice of open cholecystectomy, according to intraoperative findings and frozen pathology test results to choose the appropriate surgical procedures.