用人二倍体细胞疫苗(HDCV)在儿童中作狂犬病暴露后预防,反应发生率为1.5%,未发现神经麻痹反应。HDCV用于暴露前预防亦是安全有效的,但是医生对幼儿的应用仍迟疑不决。本文报道了用HDCV作狂犬病暴露前预防的结果。作者于1978～81年间,用HDCV对随父母到疫区的394名5个月至15岁的儿童作暴 Prevention of rabies exposure in children with human diploid cell vaccine (HDCV) was 1.5% and no paralysis was found. HDCV is also safe and effective for pre-exposure prevention, but doctors are still hesitant to use it. This article reports the results of pre-exposure prophylaxis with HDCV for rabies. From 1978 to 1981, the authors used HDCV to test the violence of 394 children aged 5 months to 15 years with their parents in the affected area