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粉防己碱(Tetrandrine)具有降压、扩张外周血管及冠状血管作用,对心脏有负性肌力和负性频率作用,并具有一定程度的预防心肌梗塞阿及抗心绞痛的疗效。本文研究其对冠脉流量,心肌营养性血流量及耗氧量的作用。 一,方法与结果 (一)离体猫心灌流实验:按Langendorff法
Tetrandrine has antihypertensive, dilated peripheral vascular and coronary vascular effects, negative cardiac muscle and negative frequency effects, and has a certain degree of efficacy in preventing myocardial infarction and anti-angina pectoris. This article studies its effect on coronary flow, myocardial nutrient blood flow and oxygen consumption. I. Methods and results (a) Isolated cat heart perfusion experiments: according to the Langendorff method