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近年来红斑性狼疮的发病率逐渐增高,临床表现复杂。目前对于其皮肤病变(即盘状型和播散型)和系统性病变之间的关系,以及前者转化为后者的可能性,尚留有不同看法。一些人认为皮肤型和系统型红斑狼疮是彼此不同的疾病;而另一些人认为,它们是由各种不同程度的自体免疫过程所致之同一疾病的不同表现。免疫学检查证实,各型红斑性狼疮患者在体液和细胞免疫方面具有一定的共同规律性,自体免疫应咎反应在不同阶段的相互关系决定着皮肤型向系统型转化的条件。据临床报道,其转化率约占0.2—
In recent years, the incidence of lupus erythematosus gradually increased, the clinical manifestations of complex. There is still a divergence of view regarding the relationship between skin lesions (discoid and disseminated) and systemic lesions, and the possibility of the former becoming the latter. Some people think skin type and systemic lupus erythematosus are different diseases, while others think that they are different manifestations of the same disease caused by various degrees of autoimmune process. Immunological tests confirmed that patients with various types of lupus erythematosus in the humoral and cellular immune have some common law, autoimmune blame the reaction in different stages of the relationship between the decision of the skin-type systems to the conditions of conversion. According to clinical reports, the conversion rate of about 0.2-