目的分析符合线路显像SPECT/CT对于诊断直肠癌,及其预后转归的临床价值,为临床提供相应的诊断依据。方法选择我院肿瘤科2011年12月-2012年7月期间入院接受治疗的直肠癌患者58例,其中28例经过活检证实为直肠癌,另30例经过手术治疗后临床怀疑具有复发可能。所有患者均实行18F-脱氧葡萄糖符合线路显像进行疾病的诊断。同时使用B超、MRI、PET进行诊断,对比不同诊断方法对患者检测结果的灵敏度、特异性、阳性预测值、阴性预测值、准确性。结果 28例直肠癌患者使用符合线路诊断得出真阳性25例,假阴性1例,无假阳性。30例直肠癌术后患者诊断得出真阳性24例,假阴性2例,无假阳性。复发转移的24例患者中16例经过手术病理证实,2例进行穿刺活检证实。另外2例在1年随访死亡,其余4例患者实行检查后给予放疗治疗。综合两组的诊断结果,得出SPECT/CT诊断真阳性49例,真阴性6例,假阳性3例,无假阴性。其诊断的灵敏度,特异性,阳性预测值,阴性预测值,准确性分别为94.2%、100%、100%、66.7%、94.8%。符合线路对于直肠癌患者的诊断及术后预后的转轨诊断结果均较B超、PET,MRI准确性高。结论使用符合线路SPECT/CT作为直肠癌的诊断及预后鉴别诊断具有较高的临床价值,可于临床广泛推广使用。 Objective To analyze the clinical value of coincidence imaging SPECT/CT in the diagnosis of rectal cancer and its prognosis, and provide corresponding diagnosis basis for the clinic. Methods A total of 58 patients with rectal cancer admitted to our hospital during the period from December 2011 to July 2012 were selected. Among them, 28 cases were rectal cancer confirmed by biopsy. The other 30 cases were suspected to have recurrence after surgical treatment. All patients underwent 18F-deoxyglucose-conformal imaging to diagnose the disease. At the same time, B-ultrasound, MRI, and PET were used for diagnosis. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of different diagnostic methods for the patient’s test results were compared. Results Twenty-five patients with rectal cancer were diagnosed as true positive by using line diagnosis. There were 1 false negative cases and no false positives. 30 cases of rectal cancer patients were diagnosed as true positive in 24 cases, false negative in 2 cases, and no false positives. Among the 24 patients with recurrence and metastasis, 16 cases were confirmed by operation and pathology, and 2 cases were confirmed by biopsy. The other 2 patients died at the 1-year follow-up, and the remaining 4 patients received radiotherapy after the examination. Based on the diagnosis results of the two groups, 49 cases were diagnosed as true positive by SPECT/CT, 6 cases were true negative, 3 cases were false positive, and there were no false negatives. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 94.2%, 100%, 100%, 66.7%, and 94.8%, respectively. The line-accurate diagnosis results for the diagnosis and postoperative prognosis of patients with rectal cancer were more accurate than B ultrasound, PET, and MRI. Conclusion The use of coincidence line SPECT/CT as a diagnostic and prognostic differential diagnosis of rectal cancer has high clinical value and can be widely used in clinical practice.