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目的:探讨准分子激光原位角膜磨镶术后干眼和屈光回退的相关性。方法:近视患者225例分别在LASIK术前及术后6mo进行Schirmer试验、泪膜破裂时间、角膜知觉和角、结膜荧光素染色检查,并接受McMonnies问卷调查。综合病史及治疗效果对结果作比较分析。结果:LASIK术后干眼和屈光回退显著相关。术后发生干眼症的32例患者中8例(25.0%)同时伴有屈光回退,而未发生干眼症的193例患者中仅18例(9.3%)伴有屈光回退,差异有极显著意义(P<0.01)。结论:LASIK术后干眼患者屈光回退的危险性增加。
Objective: To investigate the correlation between dry eye and refractive regression after excimer laser in situ keratomileusis. Methods: Schirmer test, tear film break-up time, corneal sensation and angle, conjunctival fluorescein staining were performed before and after LASIK in 225 patients with myopia. The McMonnies questionnaire was also used. Comprehensive medical history and treatment of the results for comparative analysis. Results: There was a significant correlation between dry eye and refractive regression after LASIK. Eighty patients (25.0%) of 32 patients with postoperative dry eye were accompanied by refractive regression, while only 18 (9.3%) of the 193 patients without dry eye had refractive regression, The difference was significant (P <0.01). Conclusion: The risk of refractive regression in patients with dry eye after LASIK is increased.