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21例健康人和“无症状”胆囊结石病人口服红霉素0.5g,B超分别测定服药前后空腹胆囊容量(FV)及餐后剩余容量(RV).结果示:健康组服药前后FV(ml)分别为11.20±3.36和9.36±2.79,RV(ml)为4.60±2.54和3.16±1.61;胆结石组服药前后FV(ml)分别为20.88±7.14和19.41±7.92,RV(ml)为11.68±5.37和8.08±3.93.服药前后比较差异有显著性(P<0.05～0.01).服药前后胆囊最大排空率(%)健康组分别为59.60±11.93和67.63±18.96(P>0.05);胆结石组分别为44.08±17.91和59.98±13.91(P<0.01).结论认为红霉素可促进正常人和胆囊结石患者的胆囊排空功能,并逆转部分病人的胆囊动力缺陷.
21 healthy people and “asymptomatic” patients with gallbladder stone were given orally with erythromycin 0.5g, the fasting gallbladder volume (FV) and postprandial residual volume (RV) were measured before and after taking B-mode ultrasound.The results showed that FV ) Were 11.20 ± 3.36 and 9.36 ± 2.79, respectively. The RV (ml) was 4.60 ± 2.54 and 3.16 ± 1.61 respectively. The FV (ml) in the gallstone group was 20.88 ± 7.14 and 19.41 ± 7.92, the RV was 11.68 ± 5.37 and 8.08 ± 3.93, respectively (P <0.05 ~ 0.01). The maximum rate of gallbladder emptying before and after treatment was 59.60 ± 11.93 and 67.63 ± 18.96, respectively (P> 0.05) Group were 44.08 ± 17.91 and 59.98 ± 13.91 respectively (P <0.01) .Conclusion: Erythromycin can promote the function of gallbladder emptying in patients with normal and gallbladder stones, and reverse the gallbladder power deficit in some patients.