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目的:观察脑心通胶囊对2型糖尿病患者血脂及动脉粥样硬化斑块的影响。方法:选取2型糖尿病伴高脂血症患者80例,随机分为观察组和对照组,两组均予以控制血糖等基础治疗。观察组应用阿托伐他汀10 mg晚1次口服同时加用脑心通胶囊3粒日3次口服;对照组只应用阿托伐他汀10 mg晚1次口服,治疗3个月后观察两组血脂水平及颈动脉粥样硬化斑块的变化。结果:治疗后观察组血脂水平及颈动脉内膜中层厚度,内膜斑块厚度改善均优于对照组,P<0.05,有显著差异。结论:脑心通胶囊可以改善血脂水平,抑制动脉粥样硬化斑块的发生发展。
Objective: To observe the effect of Naoxintong capsule on blood lipid and atherosclerotic plaque in type 2 diabetic patients. Methods: Eighty patients with type 2 diabetes mellitus and hyperlipidemia were randomly divided into observation group and control group, and both groups were given basic treatment such as blood glucose control. In the observation group, atorvastatin 10 mg was given orally once daily for 3 times and Naoxintong capsule 3 times daily for 3 days. In the control group, only atorvastatin 10 mg was orally administered orally once daily for 3 months and then the two groups were observed Blood lipids and carotid atherosclerotic plaque changes. Results: After treatment, the levels of lipid and the intima-media thickness of carotid artery and the thickness of intima-plaque in the observation group were better than those in the control group (P <0.05). Conclusion: Naoxintong capsule can improve blood lipid level and inhibit the development of atherosclerotic plaque.