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探讨高频通气(HFV)治疗重症新生儿急性呼吸窘迫综合征的疗效,对30例ARDS患儿的平均胎龄(38±3)周,出生体重为(3.3±0.7)kg,PBO2/FiO2≤75mmHg,需要机械通气治疗者,其中10例患儿在吸氧浓度FiO2≥0.8,动脉血氧饱和度在4 h内<0.9者改为HFv治疗。结果显示:10例患儿用HFV治疗后2 h内动脉血氧饱和度均≥0.9。动脉肺泡氧分压比(a/A)较用常频通气(CMV)组显著改善,氧合指数(01)较用CMV组明显下降,至8 h后效果更加明显。因此,对重症ARDS用CMV治疗效果差者可尝试改用HFV治疗。
To investigate the effect of high frequency ventilation (HFV) on severe neonatal acute respiratory distress syndrome (ARDS). The mean gestational age (38 ± 3) weeks, birth weight of (3.3 ± 0.7) kg, PBO2 / FiO2 75mmHg, need mechanical ventilation treatment, of which 10 cases of children in the oxygen concentration FiO2≥0.8, arterial oxygen saturation within 4h <0.9 were changed to HFv treatment. The results showed that arterial oxygen saturation was ≥0.9 within 2 hours after HFV treatment in 10 children. The ratio of arterial alveolar oxygen pressure (a / A) was significantly improved compared with the normal frequency ventilation (CMV) group. The oxygenation index (01) was significantly lower than that of CMV group, and the effect was more obvious after 8 hours. Therefore, the treatment of severe ARDS with CMV poor results can try to switch to HFV treatment.