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目的探讨腹泻患儿轮状病毒感染与肠外脏器损害的关系。方法对327例住院腹泻患儿用金标法检测粪便轮状病毒抗原并做心肌酶及肝功检测。结果观察组(粪便轮状病毒检测阳性)与对照组(粪便轮状病毒检测阴性)心肌损害及肝损害发生率比较,差异有显著性(P<0.05);观察组中,小年龄组较大年龄组心肌损害及肝功损害发生率高,有显著性差异(P<0.05);而腹泻轻重程度与心肌损害及肝损害发生率比较,无显著性差异(P>0.05)。结论轮状病毒感染常合并心肌损害及肝损害,且年龄小者受损害的几率较大。临床医生对腹泻患儿应注意粪便轮状病毒抗原及心肌酶、肝功的检测,并给予及时有针对性的治疗。
Objective To investigate the relationship between rotavirus infection and organ damage in children with diarrhea. Methods A total of 327 inpatients with diarrhea in hospital were tested for stool rotavirus antigen by gold standard method and myocardial enzymes and liver function tests were performed. Results There was a significant difference between the observation group (positive for stool rotavirus test) and the control group (negative for stool rotavirus test) in the incidence of myocardial damage and liver damage (P <0.05). In the observation group, the younger age group was larger The incidence of myocardial damage and liver damage was significantly higher in the age group than in the control group (P <0.05). There was no significant difference between the severity of diarrhea and the incidence of myocardial damage and liver damage (P> 0.05). Conclusions Rotavirus infection is often associated with myocardial damage and liver damage, and the risk of younger age is impaired. Clinicians should pay attention to children with diarrhea stool rotavirus antigen and enzyme, liver function tests, and give timely and targeted treatment.