较小的胰岛细胞瘤有时不易检出,即使应用B超、CT扫描、磁共振成像以及胰腺动脉造影等检查。门静脉血采样(PVS)的阳性率可达75％～80％,但操作烦琐,常需多个小静脉血样。作者根据动脉内注射钙剂后测定肝静脉内胰岛素浓度的原理,在9例胰岛细胞瘤病人应用这一动脉内刺激和静脉血采样(ASVS)的方法,经股静脉穿刺插管至右、左肝静脉以免遗漏位于胰头、尾部腺瘤。作标准的胰腺动脉造影,包括显影胃十二指肠动脉、近端脾动脉、肠系膜上动脉和肝固有动脉。不在胰背动脉内注射钙剂,以防胰腺炎的发生。自动脉导管注入葡萄糖酸钙0.025mEq ca~(2+)/kg(用5ml盐水稀释),在注射前和注射后30、60和 Smaller islet cell tumors are sometimes difficult to detect, even with B-ultrasound, CT scans, magnetic resonance imaging, and pancreatic angiography. The positive rate of portal vein blood sampling (PVS) can reach 75% to 80%, but the operation is cumbersome and often requires multiple small venous blood samples. Based on the principle of measuring intra-intestinal insulin concentration after intra-arterially injecting calcium, the authors applied this intra-arterial stimulation and venous blood sampling (ASVS) to 9 cases of islet cell tumors, and were cannulated to the right and left by femoral vein puncture. The hepatic veins are not left in the pancreatic head and tail adenomas. Standard pancreatic arteriography, including the development of gastroduodenal artery, proximal splenic artery, superior mesenteric artery and proper hepatic artery. Do not inject calcium into the dorsal pancreatic artery to prevent pancreatitis. Calcium gluconate 0.025mEq ca 2+ /kg (diluted with 5ml saline) was injected into the arterial catheter, before and 30, 60 and after injection