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一类新的β-内酰胺族抗生素类具有碳杂青霉烯环系统,其中的代表是硫霉素(1)。近年,由于它具有很高和广谱的抗菌活性,因此引人注目。由黄灰链霉菌的肉汤培养液中分离出表硫霉素类与橄榄色链霉菌产生的
A new class of [beta] -lactam antibiotics have a carbapenem ring system, the representative of which is thiophanmycin (1). In recent years, it attracts attention because of its high and broad-spectrum antibacterial activity. Streptomyces sp. And Streptomyces olivaceus isolated from broth culture of Streptomyces griseus