作者回顾性地研究了由同一医生观察治疗16年的62例艾森曼格综合征患者。结果 62例(女性42例,男性20例),其中17例(27％)为21三体综合征,另45例无基因异常。56例通过至少一次心导管检查确诊有体肺循环间的异常通道、肺动脉高压及右向左分流或双向分流。6例仅由心超证实。病因主要为室间隔缺损、房室共道、房间隔缺损、动脉导管末闭等。随访时间从0月到39年,平均16年。首次确诊的年龄从6个月到54岁,平均14岁。最后随访年龄(末次就诊或死亡)9～63岁,平均30±11岁,8例50岁,5例50岁以上,24例无三体征的 The authors retrospectively studied 62 patients with Eisenmenger’s syndrome treated by the same doctor for 16 years. Results 62 cases (42 females and 20 males), of which 17 (27%) had trisomy 21 and the other 45 had no gene abnormalities. Fifty-six patients were diagnosed with abnormal passages of pulmonary circulation, pulmonary hypertension and right-to-left or bilateral shunt by at least one cardiac catheterization. 6 cases confirmed only by the heart. The main causes of ventricular septal defect, atrioventricular total atrial septal defect, patent ductus arteriosus and so on. Follow-up time from 0 to 39 years, an average of 16 years. The first diagnosis of the age from 6 months to 54 years old, with an average of 14 years old. The final follow-up age (last visit or death) was 9 to 63 years, mean 30 ± 11 years, 8 cases 50 years old, 5 cases over 50 years old, 24 cases without trisomy