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目的:探讨高频电波刀电圈环切术(LEEP),治疗宫颈疾患合并高危型人乳头瘤病毒(HPV)感染的临床疗效。方法:对26例经电子阴道镜下宫颈多点活检提示高危型HPV阳性患者进行LEEP治疗,术后3个月再次检测评价其疗效。结果:阴道镜下活检病理结果与LEEP术后病理结果符合率为42.31%(11/26),两者一致性较差。术后病理级别升高12例,级别下降3例。LEEP术后3个月宫颈HPV检测转阴率为80.77%(21/26)。结论:LEEP锥切治疗宫颈疾患合并HPV感染是比较有效的一种方法,并可提高诊断的准确性,值得应用推广。
Objective: To investigate the clinical effect of high frequency electrosurgical knife ring electrosurgical excision (LEEP) in the treatment of cervical disease combined with high risk human papillomavirus (HPV) infection. Methods: Twenty - six cases of LEEP treated by multi - biopsy under electronic colposcopy prompted high - risk HPV positive patients. The curative effect was evaluated again 3 months after the operation. Results: The biopsy results of colposcopy coincided with pathological results of LEEP (42.31% (11/26)), the consistency between them was poor. Postoperative pathological grade increased in 12 cases, grade decreased in 3 cases. Cervical HPV test 3 months after LEEP negative rate of 80.77% (21/26). Conclusion: LEEP conization treatment of cervical disease combined with HPV infection is a more effective method, and can improve the diagnostic accuracy, it is worth to promote the application.