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目的探讨血清甲状旁腺激素(PTH)与β2-微球蛋白(β2-MG)对于急慢性肾衰患者的临床应用价值。方法随机选取应用血液透析治疗的急慢性肾衰患者各40例。急性肾衰组(ARE)(A组40例)、慢性肾衰组(CRF)(B组40例),同时随机选取健康查体者(C组)40例。分别检测血清PTH与β2-MG水平,随后进行统计分析。结果 B组PTH与β2-MG水平显著高于A组和C组(P<0.01)、A组β2-MG水平高于C组(P<0.05)、A组与C组PTH比较无显著性差异(P>0.05)。结论急性肾衰患者血β2-MG增高,但PTH无明显变化,慢性肾衰患者血PTH与β2-MG显著增高。
Objective To investigate the clinical value of serum parathyroid hormone (PTH) and β2-microglobulin (β2-MG) in patients with acute and chronic renal failure. Methods Forty patients with acute and chronic renal failure who were treated with hemodialysis were randomly selected. 40 cases of acute renal failure group (A group), 40 cases of chronic renal failure group (40 cases of B group) and 40 cases of healthy volunteers (C group) randomly. Serum PTH and β2-MG levels were detected, followed by statistical analysis. Results The levels of PTH and β2-MG in group B were significantly higher than those in group A and C (P <0.01), and the levels of β2-MG in group A were higher than those in group C (P <0.05). There was no significant difference in PTH between group A and group C (P> 0.05). Conclusion Serum β2-MG is elevated in patients with acute renal failure, but there is no significant change in PTH. Blood PTH and β2-MG are significantly increased in patients with chronic renal failure.