近年来,我们应用尼莫地平治疗急性蛛网膜下腔出血(SAH)昏迷31例,取得良好效果。现总结如下。 临床资料:本组59例发病6小时内,经颅脑CT检查确诊的急性SAH患者,均无糖尿病、重度肝肾功能不全、心功能不全或多脏器功能衰竭。随机分为两组,治疗组31例,男18例,女13例;年龄42～57岁,平均49岁;意识状态评分(18.19±5.64);对照组28例,其性别、年龄、意识状态评分等与治疗组具有可比性。 治疗方法:两组均采用降低颅内压、抗纤溶止血及对症支持治疗;治疗组在此基础上用尼莫地平10mg加入5％葡萄糖生理盐水250～500ml中静脉滴注,每日1次,共10天。 结果:两组治疗前后意识状态评分见表1。表1显示,两 In recent years, we use nimodipine in the treatment of acute subarachnoid hemorrhage (SAH) coma in 31 cases, and achieved good results. Now summarized as follows. Clinical data: The group of 59 patients within 6 hours of onset, the diagnosis of acute SAH by brain CT examination of patients, no diabetes, severe liver and kidney dysfunction, cardiac insufficiency or multiple organ failure. The patients in the treatment group were divided into two groups at random. The treatment group consisted of 31 patients, 18 males and 13 females, aged from 42 to 57 years (mean, 49 years). The score of conscious state was 18.19 ± 5.64. The control group had 28 males, including gender, age, Scoring and treatment group comparable. Treatment: two groups were used to reduce intracranial pressure, anti-fibrinolysis and symptomatic symptomatic treatment; the treatment group on this basis with nimodipine 10mg added 5% glucose saline 250 ~ 500ml intravenous infusion once daily , A total of 10 days. Results: The two groups before and after treatment of consciousness status score in Table 1. Table 1 shows that two