红细胞谷胱甘肽还原酶(glutathione reductase,GR)为谷胱甘肽代谢中一个重要的酶,它催化以下反应: GSSG+NADPH+H~+(?)2GSH+NADP~+ GSH(还原型谷胱甘肽)参与红细胞的氧化还原反应,对于保护红细胞不受氧化性损害,维持红细胞膜的稳定性具有重要的作用。已有人报导,GR缺乏者出现药物性溶血,而且GR缺乏还同再生障碍性贫血、白细胞减少症、血小板减少症、急性白血病、I型血友 Erythrocyte glutathione reductase (GR), an important enzyme in glutathione metabolism, catalyzes the following reactions: GSSG + NADPH + H ~ + 2GSH + NADP ~ + GSH Cytosine) is involved in the redox reaction of erythrocytes and plays an important role in protecting erythrocytes from oxidative damage and maintaining the stability of the erythrocyte membrane. It has been reported that drug-induced hemolysis occurs in people who are deficient in GR, and that deficiency in GR is associated with aplastic anemia, leukopenia, thrombocytopenia, acute leukemia, type I haemophilia