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作者报告了3例有大量真菌菌丝的孢子丝菌病的临床、病理及治疗情况.患者年龄为65、67、72岁.2例为家庭妇女,1例为农民.除1例有糖尿病史外,身体均健康.临床表现均为右前臂有结节、斑块,上有溃疡,无触痛,局部淋巴结不肿大.其中2例出疹前有局部外伤史.3例均外用过皮质类固醇软膏治疗但无效.实验室检查包括血尿常规、肝功能及多项皮肤免疫功能试验,结果几乎都在正常范围内.孢子丝菌素试验均阳性.病理示:真皮中、上部有组织细胞肉芽肿,周围绕以少量淋巴细胞及上皮样细胞,偶见中性粒细胞,无脓肿形成.在组织细胞肉芽肿中发现大量真菌,主要为大小不一的卵圆形及圆形孢子;一些能产生芽管,未发现星
The authors reported the clinical, pathological and therapeutic status of three sporotrichosis with a large number of fungal hyphae, aged 65, 67, and 72. Two were housewives and one was a farmer, except one with a history of diabetes In addition, the body is healthy.The clinical manifestations are nodules on the right forearm, plaque, ulcers, no tenderness, local lymph node enlargement.Among them 2 cases had a history of partial trauma before rash, 3 cases were used cortical Steroid ointment treatment but not effective.Laboratory tests include hematuria, liver function and a number of skin immune function tests, the results are almost all within the normal range of sporotricin test were positive.Pathology: the dermis, the upper part of the organized cell granulation Swollen, surrounded by a small amount of lymphocytes and epithelioid cells, occasionally neutrophils, abscess formation in the tissue cell granulomas found in a large number of fungi, mainly of oval and round spores of different sizes; some can Generated germ tube, no stars found