目的　探讨血液净化疗法治疗重度氟乙酰胺中毒的疗效。方法　采用血液净化加用乙酰胺治疗 16例及单用乙酰胺治疗 13例急性重度氟乙酰胺中毒患儿。结果　血液净化加用乙酰胺组 16例抢救均获得成功 ,抢救成功率为 10 0 % ,单用乙酰胺组 13例抢救成功 7例 ,抢救成功率为 5 4% ,两组有显著性差异。结论　血液净化加用乙酰胺作解毒方法的疗效优于单用乙酰胺 Objective To investigate the curative effect of blood purification therapy on severe fluoroacetamide poisoning. Methods Blood purification plus acetamide was used to treat 16 children and acetamide to treat 13 children with acute severe fluoroacetamide poisoning. Results In the blood purification plus acetamide group, all the 16 cases were successfully treated. The success rate of rescue was 10%. In the acetamide group, 13 cases were successfully salvaged, and the success rate of rescue was 54%. There was a significant difference between the two groups. Conclusion Blood purification plus acetamide as a detoxification method is superior to acetamide alone