静注纳洛酮 0 .4mg逆转阿片类药物引起的呼吸抑制时 ,如果滴速过快或剂量过大也消除阿片类药物的镇痛作用。纳洛酮还增强交感神经系统的兴奋性 ,所以可引起高血压、心动过速、室性心律失常、肺水肿 ,甚至心脏骤停。此外 ,如果病人常用阿片类药物或对这类药物有生理依赖性 ,往往 Intravenous Naloxone 0.4 mg reverses opioid-induced respiratory depression and eliminates the analgesic effects of opioids if the drip rate is too high or the dosage is too large. Naloxone also enhances the excitability of the sympathetic nervous system, so it can cause high blood pressure, tachycardia, ventricular arrhythmias, pulmonary edema, and even cardiac arrest. In addition, patients often use opioids or are physiologically dependent on such drugs