Design and Synthesis of 3,4-Dihydropyrrolo[2, 1-c][1, 4]oxazin-1-oneand its 7-Acyl Derivatives

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Starting from 1H-pyrrole, unreported 3, 4-dihydropyrrolo[2, 1-c][l, 4]oxazin-1-one 4, 7-(4-chlorobenzoyl)-3, 4-dihydropyrrolo[2, 1-c][1, 4]oxazin-1-one 5 and 7-benzoyl-3, 4-dihydro-pyrrolo [2, 1-c][1, 4]oxazin-1-one 9 were designed and synthesized. They may have antipyretic and analgesic activities. Starting from 1H-pyrrole, unreported 3,4-dihydropyrrolo [2,1-c] [1,4] oxazin-1-one 4,7- (4-chlorobenzoyl) [1, 4] oxazin-1-one 5 and 7-benzoyl-3, 4-dihydro-pyrrolo [2,1-c] [1,4] oxazin-1-one 9 were designed and synthesized. antipyretic and analgesic activities.
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