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目的分析硝苯地平联合硫酸镁治疗妊娠期高血压疾病的临床效果。方法 60例妊娠期高血压产妇,随机分为观察组和对照组,各30例。对照组给予硫酸镁治疗,观察组给予硝苯地平联合硫酸镁治疗,比较两组血压指标、疗效及妊娠结局情况。结果观察组治疗总有效率为90.0%,显著高于对照组的73.3%(P<0.05);观察组患者治疗后的血压、24 h尿蛋白定量和血液粘稠度明显优于对照组(P<0.05);观察组新生儿Apgar评分优于对照组(P<0.05)。结论硝苯地平联合硫酸镁治疗妊娠期高血压患者,疗效较单独用药更佳,可以有效控制患者血压水平,改善血液指标,从而改善妊娠结局,值得推广。
Objective To analyze the clinical effect of nifedipine combined with magnesium sulfate in the treatment of hypertensive disorder complicating pregnancy. Methods Sixty pregnant women with gestational hypertension were randomly divided into observation group and control group, with 30 cases in each group. The control group was treated with magnesium sulfate. The observation group was treated with nifedipine and magnesium sulfate. The blood pressure, efficacy and pregnancy outcome were compared between the two groups. Results The total effective rate of observation group was 90.0%, which was significantly higher than that of control group (73.3%, P <0.05). After treatment, blood pressure, 24-hour urine protein and blood viscosity in observation group were significantly better than those in control group <0.05). Apgar score in observation group was better than that in control group (P <0.05). Conclusion Nifedipine combined with magnesium sulfate treatment of hypertensive patients with gestational hypertension, better than single medication, which can effectively control the patient’s blood pressure levels, improve blood parameters, thereby improving pregnancy outcomes, it is worth promoting.