50年代Du Vigneaud 首次合成了催产素,因而获得了诺贝尔奖,从此产科有了一种较纯的促子宫收缩药物,用于临床引产及催产,起到了为产妇及胎婴儿造福的作用。如今30多年过去了,医学及产科方面都有了长足的进步,但是催产素仍是引产的首选药物。一、催产素引产的适应证1.妊高征:作者1985年曾对南京鼓楼医院产科应用催产素引产的指征作了一次回顾性的分析.发现虽然妊高征、过期妊娠及胎膜早破是历年引产的主要三大指征,但是比例却有所变化。50年代妊高征占首位,70年代虽仍为首位,但比例已与胎膜早 In the 1950s Du Vigneaud first synthesized oxytocin, which won the Nobel Prize, from obstetrics there is a more pure uterine contraction drugs for clinical induction and oxytocin, played a role in the benefit of mothers and fetuses. Now more than 30 years have passed. There have been great advances in medicine and obstetrics, but oxytocin is still the drug of choice for induction of labor. First, the indications of oxytocin induction of labor 1. PIH: The author of Nanjing Drum Tower Hospital obstetric application of oxytocin induction of indications made a retrospective analysis in 1985 found that although pregnancy-induced hypertension, premature pregnancy and premature rupture of membranes Breaking is the main three major indications of abortion in the calendar year, but the proportion has changed. Pregnancy-induced hypertension in the 50s occupy the first place, although the 70s is still the first place, but the proportion has been with the premature rupture of membranes