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目的:分析头孢菌素类药物不良反应及临床分析。方法:回顾性分析我院发生头孢菌素类药物不良反应26例患者的临床资料,总结发生不良反应的原因及其临床表现。结果:头孢菌素类抗菌药物在临床中的运用,存在多种不良反应,包括神经系统反应、血液系统反应、泌尿系统反应、变态反应等。而患者身患疾病、不合理用药、药物用量不当以及服药后饮酒等都是导致不良反应发生的原因。结论:头孢菌素类药物不良反应及其发生因素较多,在用药过程中必须加强预防,同时制定临床用药规范,有效地控制不良反应发生率。
Objective: To analyze the adverse reactions and clinical analysis of cephalosporins. Methods: The clinical data of 26 patients with adverse reactions of cephalosporins in our hospital were retrospectively analyzed. The causes and clinical manifestations of the adverse reactions were summarized. Results: There are many side effects of cephalosporin antimicrobials in clinical application, including nervous system reaction, hematological response, urinary system reaction and allergic reaction. The patients suffering from diseases, irrational medication, improper use of drugs and taking alcohol and so are the causes of adverse reactions. Conclusion: The cephalosporins have many adverse reactions and their occurrence factors. In the process of medication, we must strengthen the prevention, and at the same time, formulate the standard of clinical medication and effectively control the incidence of adverse reactions.