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目的探讨肺炎衣原体(CP)感染与高血压的关系以及与高血压的传统危险因素的交互作用对高血压的影响。方法选取内蒙古自治区14个村蒙古族居民1430人,其中高血压患者488例,非高血压者942人。采用ELISA法检测血清中的特异性CP IgG抗体。应用SPSS 13.0软件进行统计分析。结果高血压组和非高血压组间,CP IgG阳性率的分布差异有统计学意义,但调整年龄、性别、饮酒、吸烟、BMI和血脂异常后,这种显著性关联不存在;研究发现CP感染和性别、超重、血脂异常的交互作用与蒙古族高血压有关联,其OR值分别为13.916、5.785和2.935。结论CP感染与蒙古族高血压无关联,但与高血压的其他传统危险因素有交互作用,可使蒙古族人群患高血压的危险性增加。
Objective To investigate the relationship between the infection of Chlamydia pneumoniae (CP) and hypertension and its interaction with traditional risk factors of hypertension on hypertension. Methods 1430 Mongolian residents in 14 villages of Inner Mongolia Autonomous Region were selected, including 488 cases of hypertension and 942 cases of non-hypertension. Serum specific IgG antibodies were detected by ELISA. Application SPSS 13.0 software for statistical analysis. Results There were significant differences in the distribution of CP IgG positive rates between hypertensive and nonhypertensive groups, but no significant association was found after adjusting for age, sex, alcohol consumption, smoking, BMI and dyslipidemia. The study found that CP The correlation between infection and gender, overweight and dyslipidemia was associated with Mongolian hypertension with ORs of 13.916, 5.785 and 2.935, respectively. Conclusion CP infection is not associated with Mongolian hypertension, but interacts with other traditional risk factors of hypertension, which may increase the risk of hypertension in Mongolian population.