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前列腺素(PGs)是眼睛在受各种刺激之后在眼内产生的,并被认为是由于炎性反应所介导.在前列腺素的几种类型中,PGE和PGF与眼内压(IOP)的关系已经有了广泛的研究.早期的研究认为这些化合物是升高眼压的.然而,近来的研究认为在许多动物种属中局部应用这些药物最终是降低IOP的.不过大剂量可致兔和猴子眼内压在最初升高.而且致兔和猫的房闪阳性.
Prostaglandins (PGs) are produced by the eye in the eye after various stimuli and are thought to be mediated by inflammatory responses In several types of prostaglandins, PGE and PGF interact with intraocular pressure (IOP) Of the relationship has been extensive research earlier studies that these compounds are elevated intraocular pressure.However, recent studies suggest that topical application of these drugs in many animal species eventually reduce IOP, but the large dose can cause rabbits Intraocular pressure in the monkey and the initial increase in. But also to rabbit and cat room flash positive.