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目的观察低分子肝素治疗冠心病不稳定型心绞痛的临床疗效。方法传统抗心绞痛药阿司匹林治疗不佳的不稳定型心绞痛患者46例加用低分子肝素皮下注射5000 u次/,1次/12 h,连用7d。结果加用低分子肝素的46例患者与治疗前相比,其心绞痛发作频率明显减少,发作间隔时间延长,心电图及动态心电图心肌缺血明显改善,减少了急性期心肌缺血事件和心律失常的发生,未见明显不良反应。结论低分子肝素加阿司匹林治疗不稳定型心绞痛疗效满意、可靠、安全。
Objective To observe the clinical effect of low molecular weight heparin in the treatment of unstable angina pectoris. Methods Forty-six patients with unstable angina pectoris treated with traditional anti-anginal medicine aspirin were treated with subcutaneous injection of low-molecular-weight heparin 5000 u times a day for 12 days for 7 days. Results Compared with those before treatment, 46 patients with low molecular weight heparin had significantly lower frequency of angina pectoris, longer interval between seizures, significantly improved electrocardiogram and Holter myocardial ischemia, and decreased acute myocardial ischemia and arrhythmia Occurred, no obvious adverse reactions. Conclusion Low molecular weight heparin and aspirin are effective, reliable and safe for the treatment of unstable angina pectoris.