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目的探讨降钙素原联合C-反应蛋白检测对血液病感染患者的临床意义。方法60例血液病感染患者，根据所感染微生物种类的不同，分为革兰阳性菌感染组(21例)、革兰阴性菌感染组(22例)、真菌感染组(17例)，检测患者的降钙素原和C反应蛋白水平。结果60份血培养标本中，革兰阳性菌21株、革兰阴性菌22株、真菌17株；革兰阳性菌感染组、革兰阴性菌感染组的PCT水平显著高于真菌感染组(0.05)；单独检测CRP，其特异性与敏感性分别为65.99%与85.27%，而PCT联合CRP检测的特异性与敏感性分别为85.11%与82.33%，单独检测的敏感性虽高于联合检测，但特异性较低，不能对病原菌做出准确判断。结论 PCT联合CRP检测在血液病细菌感染中具有重要价值。“,”Objective To investigate the clinical significance of the detection of serum levels of C-reactive protein in patients with hematological diseases.Methods 60 cases of blood disease infected patients,according to the infection of different microbial species,divided into leather of gram positive bacteria infection group (21 cases),leather gram negative bacteria infection group (22 cases),fungal infection group (17 cases),the detection of patients with calcitonin fibrinogen and C-reactive protein levels.Results 60 blood culture specimens,and 21 strains,leather gram negative bacteria 22 strains,17 strains of fungi of gram positive bacteria;leather of gram positive bacteria infection group,leather group of gram negative bacterial infections PCT level was significantly higher than that of fungal infection group ( 0.05);separate detection of CRP,the specificity and sensitivity were 65.99%and 85.27%,and the specificity and sensitivity of the detection of PCT and CRP were 85.11%and 82.33%,although the separate detection sensitivity is higher than joint detection,but low specificity,not to the pathogen make accurate judgments.Conclusion PCT combined with CRP detection is of great value in the bacterial infection of blood disease.