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目的调查分析我院门诊抗菌药物使用现状,分析不合理用药,提高临床合理用药水平。方法随机抽取我院2007年至2008年门诊处方每月100张,共2400张处方,根据处方评价表统计门诊处方抗菌药使用百分率、抗菌药物联合用药情况;随机抽取2007年下半年和2008年下半年门诊抗菌药物处方600张,统计抗菌药物消耗总金额、数量,进行用药频度(DDDs)和金额排序[1],对抗菌药物使用的合理性进行回顾性分析。结果我院2007年门诊抗菌药物百分率为52.3%,联合用药占抗菌药物总使用率的16.72%,2008年分别为42.6%和15.66%,呈下降趋势;2007年和2008年抗菌药物DDDs排序位于前2位药物都是头孢菌素类、喹诺酮类。结论应加强抗菌药物合理使用的监管,合理使用抗菌药物,减少耐药菌的发生,减少不良反应。
Objective To investigate and analyze the status of antimicrobial use in outpatient clinics in our hospital, to analyze the unreasonable use of drugs and to improve the clinical reasonable medication level. Methods A total of 2400 prescriptions per day were randomly selected from outpatients in our hospital from 2007 to 2008, and the percentage of antibacterials used in outpatient prescriptions and the combination of antibacterials were calculated according to the prescription evaluation form. In the second half of 2007 and the second half of 2008, Six months outpatient antibacterial prescription 600, the total amount of antimicrobial consumption statistics, the frequency of medication (DDDs) and the amount of sorting [1], the rational use of antibacterial drugs were retrospectively analyzed. Results The percentage of outpatient antibacterials in our hospital in 2007 was 52.3%. The combined use of drugs accounted for 16.72% of the total antibacterials utilization rates in 2008 and 42.6% and 15.66% respectively in 2008, showing a decreasing trend. In 2007 and 2008, 2 drugs are cephalosporins, quinolones. Conclusion The rational use of antimicrobial agents should be strengthened supervision, rational use of antimicrobial agents to reduce the incidence of drug-resistant bacteria and reduce adverse reactions.