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目的 探讨食管癌术后放疗后复发转移的危险因素.方法 回顾性分析福建省肿瘤医院放疗科收治的食管癌术后患者,行术后放疗[1、2]后,随访出现复发转移的198例,研究各观察指标与复发转移的关系.结果 198例出现复发转移的患者中,其中166例(84%)患者为2年内出现,2年内复发转移的患者中,野内复发43例(26%),尤其是半年内复发的88例患者中,仅有野内复发18例(20%),野内复发率明显低于野外复发转移.多因素分析结果表明,N分期及放疗开始时间是食管癌术后放疗后复发的危险因素,结论 术后病理淋巴结转移个数、放疗开始时间是食管癌术后放疗后复发转移的主要危险因素.
Objective To investigate the risk factors for recurrence and metastasis of postoperative radiotherapy for esophageal cancer.Methods Retrospective analysis of postoperative patients with esophageal cancer admitted to radiotherapy department of Fujian Cancer Hospital, 198 cases of recurrence and metastasis were followed up after radiotherapy [1,2] , And the relationship between each observation index and recurrence and metastasis was studied.Results Of the 198 patients with recurrence and metastasis, 166 (84%) patients were diagnosed within 2 years and 43 patients (26%) were relapsed in 2 years , Especially among the 88 patients relapsed within six months, only 18 cases (20%) had intra-field recurrence, and the recurrence rate in field was significantly lower than that in field recurrence and metastasis.Multivariate analysis showed that N-stage and radiotherapy started after esophagectomy Risk factors for relapse after radiotherapy, Conclusion The number of postoperative pathological lymph node metastases, radiotherapy start time esophageal cancer recurrence and metastasis after radiotherapy is the main risk factor.