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我们发现按中国药典(1985年版.二部.639页)收载的磺胺甲基异噁唑含量测定方法,磺胺甲基异噁唑根本不能溶解在盐酸溶液(1→2)中。磺胺甲基异噁唑虽为两性化合物,可溶于酸或碱
We found that sulfamethoxazole was not dissolved in hydrochloric acid solution (1 → 2) at all according to the method for the determination of sulfamethoxazole contained in the Chinese Pharmacopoeia (1985 edition. 2 pp. 639). Sulfamethoxazole although amphoteric compounds, soluble in acid or alkali