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目的：探讨肝肺综合征（HPS）临床诊断与治疗。方法：通过症状、体征、肺功能检查、血气分析及99m锝巨凝白蛋白（99mTcMAA）肺扫描等检查方法对21例HPS患者进行了临床观察。结果：HPS常有运动性呼吸困难，平卧呼吸、紫绀等临床表现，肺上均可见放射性缺损或减弱现象，未发现肺外器官标记，有直立性脱氧及变化程度较大的低氧血症。常规保肝治疗1～3月后，85．7％随肝功能恢复临床症状、肺放射性病变、低氧血症及直立性脱氧恢复正常。直立位氧分压及氧分压差治疗前后有显著差异性。结论：大部分HPS在早期能防肝功能恢复而自然痊愈．少数患者不能恢复，远期预后不良。
Objective: To investigate the clinical diagnosis and treatment of hepatopulmonary syndrome (HPS). METHODS: Twenty-one patients with HPS underwent clinical examination through symptoms, signs, pulmonary function tests, blood gas analysis and 99m Tc 99m TcMAA lung scan. Results: HPS often had exercise-induced dyspnea, supine breathing, cyanosis and other clinical manifestations. All of them showed radioactive defects or attenuation on the lungs. No extrapulmonary organ markers were found, there was orthostatic deoxygenation and hypoxemia . After 1 to 3 months of routine liver protection treatment, 85.7% returned to normal with recovery of liver function, lung radiological disease, hypoxemia and upright deoxygenation. Orthostatic oxygen partial pressure and partial pressure of oxygen before and after treatment were significantly different. Conclusion: Most HPS can heal spontaneously in the early stage of anti-liver function recovery. A small number of patients can not be recovered, the long-term prognosis is poor.