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认知促进药物是一类可以增强和改善认知能力的药物。该类药物目前除应用于改善疾病导致的认知损害(如阿尔茨海默病、儿童注意力缺陷多动障碍症及睡眠障碍性疾病等)之外,部分健康成年人因职业需要(如战争状态的军人、夜班工作者等)对该类药物的需求也日趋增加。本文将就该类药物目前的临床应用资料进行总结,并对处于临床前研究阶段针对不同靶点的新型认知促进药物进行分类介绍。
Cognitive-enhancing drugs are a class of drugs that enhance and improve cognitive ability. These drugs are currently used in addition to improving the cognitive impairment caused by the disease (such as Alzheimer’s disease, children’s attention deficit hyperactivity disorder and sleep disorders, etc.), some healthy adults due to occupational needs (such as war The state of servicemen, night shift workers, etc.) the demand for such drugs is also increasing. This article will summarize the current clinical application of these drugs, and classify new cognitive-promoting drugs that target different targets in preclinical studies.