纳洛酮(Naloxone)是阿片类药物和内源性阿片样物质的特异性拮抗剂,至今在临床上尚少应用,国外主要用于治疗阿片类药物过量引起的呼吸抑制,并作为检出潜在阿片瘾患者的诊断剂。近三年来,Holaday等陆续报道纳洛酮对于动物实验性休克有良好效果,此发 Naloxone, a specific antagonist of opioids and endogenous opioids, has so far been rarely used clinically abroad mainly for the treatment of opioid-induced respiratory depression and as a potential Ophthalmic addiction diagnosis of patients. In the past three years, Holaday et al reported that naloxone has a good effect on animal experimental shock,