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目的分析夫西地酸钠在革兰阳性球菌(G+球菌)感染患儿中的应用效果及合理性。方法选择2015年1月-2016年1月在医院儿科就诊并采用注射用夫西地酸钠静脉滴注治疗的G+球菌感染患儿50例,对所有患儿的治疗效果及不良反应进行观察,分析夫西地在G+球菌感染患儿用药中的合理性及有效性。结果 50例患儿中治疗总有效率为90.00%;细菌转阴率为84.00%;其中出现不良反应2例,不良反应发生率为4.00%。不良反应主要表现为静脉炎,与药物浓度高、静脉滴注速度过快、年幼患儿好动等因素有关,减缓静脉滴注速度、局部硫酸镁热敷后症状随即缓解。结论夫西地治疗G+球菌感染患儿疗效确切,细菌清除率高,不良反应较低。在使用时应明确患儿合理的溶媒量,静脉滴注时速度要慢,固定好患儿,减少静脉炎发生率,提高用药的安全性。
Objective To analyze the effect and rationality of sodium fusidate in children with gram-positive cocci infection. Methods From January 2015 to January 2016, 50 pediatric patients with G + cocci infection were treated in our hospital for pediatric patients with Fusidate sodium injection. All the children were followed up for treatment and adverse reactions. Analysis of Fusi G + cocci infection in children with the rationality and effectiveness. Results The total effective rate was 90.00% in 50 cases. The negative rate of bacteria was 84.00%. There were 2 adverse reactions and the incidence of adverse reactions was 4.00%. Adverse reactions mainly manifested as phlebitis, and high concentrations of drugs, intravenous infusion rate is too fast, young children and other factors related to ease, slow down the rate of intravenous drip, local magnesium sulfate symptoms immediately relieve symptoms. Conclusion Fusidi treatment of G + cocci infection in children with exact effect, bacterial clearance rate, low adverse reactions. In the use of children should be clear when a reasonable amount of vehicle, intravenous infusion rate to slow, fixed good children, reduce the incidence of phlebitis, improve the safety of medication.